T. Sasaki et al., EPIDEMIOLOGIC-STUDY OF MYCOPLASMA-PNEUMONIAE INFECTIONS IN JAPAN BASED ON PCR-RESTRICTION FRAGMENT LENGTH POLYMORPHISM OF THE P1 CYTADHESINGENE, Journal of clinical microbiology, 34(2), 1996, pp. 447-449
Two hundred fifty strains of Mycoplasma pneumoniae isolated during the
past 20 years in Japan were classified into two groups (I and II) bas
ed upon different PCR-restriction fragment length polymorphism pattern
s of their P1 cytadhesin genes. Clear shifts between the IM. pneumonia
e groups were observed but did not; appear to be correlated with M. pn
eumoniae epidemic cycles. Patients' sera showed relatively higher leve
ls of antiadhesin antibodies to M. pneumoniae strains homologous with
the infecting strain.