A 30-year-old man with multiseptate gallbladder, a very rare congenita
l anomaly, is presented. His presenting symptom was epigastric pain. A
hypoplastic gallbladder with multiple septa was demonstrated by ultra
sonography and endoscopic retrograde cholangiography. An injection of
cerulein reproduced pain, and simultaneous biliary manometry and scint
igraphy showed impairment of gallbladder filling and emptying. Laparos
copic cholecystectomy resulted in complete relief of the pain. Biliary
manometry and scintigraphy are useful to determine the operative indi
cation in a symptomatic patient with this entity.