EOSINOPHIL GRANULOCYTIC SARCOMA IN A NEW-ZEALAND WHITE-RABBIT

An 18-month-old New Zealand White rabbit developed a rapidly growing f irm perianal mass. Within 2 months, the mass increased in size from 4. 0 x 2.0 cm to 7.5 x 7.0 x 3.5 cm. Cut surfaces of the mass were white to yellow with foci of hemorrhage. Histopathologic examination reveale d neoplastic granulocytes that invaded the dermis of the overlying ski n, subcutaneous tissue, and the regional skeletal muscle. The tumor wa s comprised of myeloid cells with large eosinophilic cytoplasmic granu les that had the histochemical and ultrastructural features of eosinop hils. This is the first report of an eosinophil granulocytic sarcoma i n lagomorphs.