Ga. Machin et F. Bamforth, ZYGOSITY AND PLACENTAL ANATOMY IN 15 CONSECUTIVE SETS OF SPONTANEOUSLY CONCEIVED TRIPLETS, American journal of medical genetics, 61(3), 1996, pp. 247-252
Most triplets are trizygotic because they result from assisted reprodu
ction, Prognosis is generally good, We analyzed 15 sets of triplets wh
o were conceived spontaneously, Six sets were monozygotic, 7 were dizy
gotic, and only 2 sets were trizygotic. Considered as 45 twin pairs, 2
5 pairs (56%) were monozygotic, Twenty percent of these twins died as
a result of twin-twin transfusion, Spontaneously conceived triplets ha
ve high risks compared with those resulting from assisted reproduction
, These risks result from a high proportion of monozygotic embryos, ma
ny of whom have monochorionic placentas with vascular anastomoses, cau
sing twin-to-twin transfusion. (C) 1996 Wiley-Liss, Inc.