TRANSDUCTION MECHANISMS FROM BIOLOGICAL-MEMBRANES TO SILICON SENSORS - MODELING AND COMPUTER-SIMULATIONS

Authors
GRATTAROLA M MARTINOIA S MASSOBRIO G BOVE M CICCARELLI C
Citation
M. Grattarola et al., TRANSDUCTION MECHANISMS FROM BIOLOGICAL-MEMBRANES TO SILICON SENSORS - MODELING AND COMPUTER-SIMULATIONS, Molecular crystals and liquid crystals science and technology. Section A, Molecular crystals and liquid crystals, 234, 1993, pp. 645-652
Citations number
6
Categorie Soggetti
Crystallography
Journal title
Molecular crystals and liquid crystals science and technology. Section A, Molecular crystals and liquid crystals → ACNP
ISSN journal
1058725X
Volume
234
Year of publication
1993
Pages
645 - 652
Database
ISI
SICI code
1058-725X(1993)234:<645:TMFBTS>2.0.ZU;2-N
Abstract
A hybrid system consisting of a biological membrane (including an enzy me complex) in proximity (1 -10nm) to an ISFET is modelled. The respon se of the microelectronic device to a H+ production, resulting from th e enzyme-mediated transduction of a chemical signal, is simulated. Bot h steady and transient conditions are considered. Finally, hypothetica l chemical mechanisms resulting in output switching phenomena are brie fly discussed.