Primary testicular lymphoma (PTL) is the most frecuently diagnosed tes
ticular tumor in men over 60 years, in spite of this circumstance it i
s a rare process, Two cases of PTL are reported, the first one in a ch
ild and the second in an adult. Both cases were intermediate grade lym
phoma and had low stage (I(E)A), presenting initially as an enlargemen
t of the testicle as the only symptom, the second case presented invol
vement by contiguity of the abdominal muscles. Immunohistological mark
ers showed T nature in the first case, and B in the second. The treatm
ent applied in both cases was orchiectomy and systemic chemotherapy us
ing COP-BLAM/IMVP-16, in the child prophylaxis of the central nervous
system using methotrexate was made. Response to treatment was good, th
e first patient achieved complete remission and his survival at presen
t is 24 months, the second patient died 5 month after diagnosis due to
stroke without having completed chemotherapy but with an important re
duction of the tumoral mass, A review of the literature on clinical, d
iagnostic and therapeutic issues is made.