The prevalence of silent ischemia increases with age. The studies revi
ewed here show that silent ischemia is an independent predictor of new
coronary events in patients with stable coronary artery disease with
or without angina pectoris, and that the presence or absence of angina
pectoris does not significantly change the prognosis in patients with
silent ischemia. Reduction of silent ischemia by beta-blocker therapy
is associated with a decrease in coronary events.