MATERNAL SERUM SCREENING FOR FETAL DOWN-SYNDROME IN IVF PREGNANCIES

Authors
RIBBERT LSM KORNMAN LH DEWOLF BTHM SIMONS AHM JANSEN CAM BEEKHUIS JR MANTINGH A
Citation
Lsm. Ribbert et al., MATERNAL SERUM SCREENING FOR FETAL DOWN-SYNDROME IN IVF PREGNANCIES, Prenatal diagnosis, 16(1), 1996, pp. 35-38
Citations number
17
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
16
Issue
1
Year of publication
1996
Pages
35 - 38
Database
ISI
SICI code
0197-3851(1996)16:1<35:MSSFFD>2.0.ZU;2-C
Abstract
To assess the influence of in vitro fertilization (IVF) on maternal se rum human chorionic gonadotrophin (hCG) and alpha-fetoprotein (AFP), t he maternal serum hCG and AFP values were studied in 67 IVF pregnancie s and compared with the results of a control group of 4732 spontaneous ly conceiving patients. Maternal serum hCG was significantly higher an d AFP significantly lower in the IVF group. Possible explanations and implications for prenatal diagnosis in IVF pregnancies are discussed.