Purpose: To design, construct, and commission a multirod collimator fo
r producing irregularly shaped fields in neutron radiation therapy. To
demonstrate the reliability and applicability of this device to routi
ne use with a superconducting cyclotron for neutron therapy. Methods a
nd Materials: A multirod collimator has been designed, constructed, an
d thoroughly tested to investigate its radiological properties; neutro
n transmission characteristics, beam profiles, and penumbral widths as
a function of field size and depth in a phantom, and the spatial reso
lution of the rod array, have been measured. A wide variety of irregul
arly shaped fields, used routinely in neutron radiation therapy, have
been produced, including fields that incorporate partial transmission
blocks. The performance of the collimator has been closely monitored o
ver a period of 20 months to accurately assess reliability. Results: T
he multirod collimator has been in routine use for 32 months, and duri
ng this time a total of 7025 neutron fields has been treated. For the
latter 20 months of this period, detailed performance records show tha
t collimator failure has caused 28.4 h of downtime during the patient
treatment day. Only 5.25 h of this downtime was experienced in the las
t 12 months (0.22% of the available treatment time). The results of co
llimator attenuation and beam profile measurements show that the radio
logical properties of the collimator are comparable to those of other
collimator systems used for neutron radiation therapy. Isodose measure
ments in a water phantom show that the spatial resolution of the rods
is superior to that of the leaves used in neutron multileaf collimator
s. The ability of the multirod collimator to produce many irregularly
shaped fields commonly encountered in neutron radiation therapy has be
en demonstrated. Shaped fields for prostate, head and neck, soft tissu
e sarcomas, lung, thyroid, rectum, bladder, colon, breast, pancreas, a
cid gynecological tumors have been produced. For some prostate cases,
the device has been used to produce partial transmission blocks. Concl
usions: A novel multirod collimator has been designed, constructed, an
d successfully applied in the routine treatment of neutron radiation t
herapy patients.