KINETIC-BEHAVIOR OF ACTIVATION OF THERMOLYSIN BY NORMAL-ALCOHOLS

Authors
ALAM MN TADASA K KAYAHARA H
Citation
Mn. Alam et al., KINETIC-BEHAVIOR OF ACTIVATION OF THERMOLYSIN BY NORMAL-ALCOHOLS, Biotechnology letters, 18(1), 1996, pp. 45-50
Citations number
9
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
18
Issue
1
Year of publication
1996
Pages
45 - 50
Database
ISI
SICI code
0141-5492(1996)18:1<45:KOAOTB>2.0.ZU;2-O
Abstract
This paper reports an insight into the kinetic mechanism of activation and then inhibition in a thermolysin - catalyzed peptide synthesis of dipeptide (benzyloxycarbonyl)-L-phenylalanyl-L-phenylalanine methyl e ster in aqueous - organic one phase system containing n-alcohols as ac tivator. The jump in catalytic efficiency - as an effect of alcoholic solvents and the kinetic mode of activation are discussed.