Hp. Castro et al., CHANGES IN THE CELL-MEMBRANE OF LACTOBACILLUS-BULGARICUS DURING STORAGE FOLLOWING FREEZE-DRYING, Biotechnology letters, 18(1), 1996, pp. 99-104
The mechanism of inactivation of freeze-dried Lactobacillus bulgaricus
during storage in maltodextrin under controlled humidity was investig
ated. Evidence is presented supporting the hypothesis that membrane da
mage occurs during storage. A study ore the lipid composition of the c
ells by gas chromatography showed a decrease in the unsaturated and sa
turated fatty acid content of the cell. Further evidence indicating me
mbrane damage includes a decrease in membrane bound proton-translocati
ng ATPase activity.