SIMIAN VARICELLA VIRUS-ANTIBODY RESPONSE IN EXPERIMENTAL-INFECTION OFAFRICAN-GREEN MONKEYS

Authors
GRAY WL GUSICK NJ FLETCHER TM SOIKE KF
Citation
Wl. Gray et al., SIMIAN VARICELLA VIRUS-ANTIBODY RESPONSE IN EXPERIMENTAL-INFECTION OFAFRICAN-GREEN MONKEYS, Journal of medical primatology, 24(4), 1995, pp. 246-251
Citations number
27
Categorie Soggetti
Zoology,"Veterinary Sciences
Journal title
Journal of medical primatology → ACNP
ISSN journal
00472565
Volume
24
Issue
4
Year of publication
1995
Pages
246 - 251
Database
ISI
SICI code
0047-2565(1995)24:4<246:SVVRIE>2.0.ZU;2-Y
Abstract
The humoral immune response to simian varicella virus (SVV) was invest igated following primary and secondary experimental infection of Afric an green monkeys. Neutralization and immunoprecipitation assays were u sed to determine antibody titers to SVV throughout the course of infec tion. The immune response to specific viral polypeptides was analyzed by immunoprecipitation analysis. The results demonstrate that the simi an varicella model offers a useful approach to investigate immune mech anisms in human varicella tester virus (VZV) infections.