Rc. Baker et al., PH-CONTROLLED FERMENTERS TO INCREASE PRODUCTION OF LEUCONOCIN-S BY LEUCONOSTOC-PARAMESENTEROIDES, Process biochemistry, 31(3), 1996, pp. 225-228
The production of leuconocin S, a bacteriocin from Leuconostoc parames
enteroides OX, was examined during batch fermentations at pH 6.0, 6.5,
7.0 and 7.5. The specific growth rate and bacteriocin titers were hig
hest at pH 7.0, with values of 0.33 h(-1) and 20 000 AU/ml, respective
ly. Maximum bacteriocin production corresponded to late logarithmic-ea
rly stationary growth phase. Bacteriocin levels decreased during late
stationary phase, possibly due to proteolytic enzymes produced during
this period.