R. Snow et al., IS THERE ANY CONNECTION BETWEEN A 2ND PNEUMONIA SHOT AND HOSPITALIZATION AMONG MEDICARE BENEFICIARIES, Public health reports, 110(6), 1995, pp. 720-725
TO LEARN WHETHER the risk of revaccination in adults should limit its
use, the authors investigated whether adverse events requiring hospita
lization occurred in a group of Medicare enrollees revaccinated with p
neumococcal polysaccharide vaccine. A prospective cohort analysis and
case study of revaccinated people involved five percent of all elderly
Medicare enrollees from 1985 through 1988, consisting of 66,256 peopl
e receiving one dose of vaccine and 1,099 receiving two doses. Compari
son was made of the hospitalization rate within 30 days after revaccin
ation and rates of singly vaccinated persons using discharge diagnosis
for all those hospitalized during the 30 days after revaccination. No
significant difference was found between the hospitalization rate of
the revaccinated cohort and comparison group. No adverse reactions att
ributable to pneumococcal polysaccharide vaccine causing hospitalizati
on were identified among 39 revaccinated persons who were hospitalized
within 30 days of revaccination. Revaccination of elderly Medicare be
neficiaries does not cause events serious enough to require hospitaliz
ation. Vaccination of persons according to the Public Health Service i
mmunization Practice Advisory Committee guidelines is recommended when
the prior immunization status is unknown.