BIOREGULATION OF AFLATOXIN BIOSYNTHESIS BY UNIRRADIATED AND IRRADIATED CONIDIA OF ASPERGILLUS-FLAVUS

Authors
AZIZ NH ABUSHADY MR ELFOULY MZ MOUSSA LA
Citation
Nh. Aziz et al., BIOREGULATION OF AFLATOXIN BIOSYNTHESIS BY UNIRRADIATED AND IRRADIATED CONIDIA OF ASPERGILLUS-FLAVUS, Microbios, 84(338), 1995, pp. 29-39
Citations number
22
Categorie Soggetti
Microbiology
Journal title
Microbios → ACNP
ISSN journal
00262633
Volume
84
Issue
338
Year of publication
1995
Pages
29 - 39
Database
ISI
SICI code
0026-2633(1995)84:338<29:BOABBU>2.0.ZU;2-A
Abstract
A sequential technique involving the transfer of mycelia from peptone- based, aflatoxin-non-supporting medium to glucose based, aflatoxin-sup porting medium was used to study the effect of gamma-irradiation on th e regulation of aflatoxin biosynthesis by Aspergillus flavus. Analysis indicated that irradiation at a dose of 1.00 kGy produced enhancement of aflatoxin biosynthesis in peptone-glucose mineral salt cultures wi th an increase of adenine nucleotide levels and fatty acid patterns of microsomes and mitochondria. The results suggest that aflatoxin synth esis is not regulated by the overall energy status of the fungal cell but that lipoperoxidation by gamma-irradiation plays a role in aflatox in biosynthesis.