The torque generated during a passive movement of the knee joint was u
sed to quantify muscle tone in normal able-bodied subjects and spastic
and flaccid spinal cord injury (SCI) subjects using a computerized is
okinetic dynamometer. Maximum peak (T-max) and the sum of four consecu
tive peaks (T-sum) were calculated for each velocity (30, 60, 120 degr
ees/s) and for each phase (flexing or extending) separately and compar
ed statistically using a one-way ANOVA, Statistical significance betwe
en groups was found in T-max FLEXION (FLX) at 60 and 120 degrees/3. Sc
heffe's tests revealed that the spastic group was significantly less t
han both the flaccid and normal groups, although the flaccid and norma
l groups were not significantly different from each other. The slopes
of the linear regression curve of the torque-velocity data were found
and compared statistically using a t-test for parallelism. In all para
meters, the data increased in a linear fashion with increasing velocit
y of knee motion. The slope of the regression curve for the spastic gr
oup was significantly lower than that of the normal group for T-max an
d was significantly lower than that of the flaccid group for T(sum)sig
nificantly lower than that of the flaccid group for Tsum while the slo
pes for the flaccid and normal groups were not significantly different
. The ability of the entire set of variables to classify subjects into
three groups (normal, spastic, and flaccid) was tested using discrimi
nant analysis. By taking into account 7 of the 12 original variables,
this multivariate technique correctly classified 100% of the spastic,
90% of the normal, but only 67% of the flaccid subjects. Separation of
observations was between spastic and normal subjects was good, except
for only one case. This feature could be useful when dealing with ass
essment of individual responses to therapeutic interventions aimed at
modification of spasticity.