Jw. Marshall et al., STUDIES OF VENTILATION EFFICIENCY IN A PROTECTIVE ISOLATION ROOM BY THE USE OF A SCALE-MODEL, Infection control and hospital epidemiology, 17(1), 1996, pp. 5-10
OBJECTIVE: To assess the ability of a protective isolation room ventil
ation system to reduce patient exposure to airborne infectious agents,
using a small-scale model that permits cost-effective and unobtrusive
study of relevant indices of performance. DESIGN: A one-half scale mo
del of a protective isolation room at the University of Minnesota Hosp
ital was constructed and equipped for tracer gas experiments to assess
ventilation efficiency. MEASUREMENTS: Tracer gas (SF6) was injected i
nto the model supply air. Tracer gas concentration was recorded over t
ime and analyzed to determine local and room mean age of air. Age of a
ir is a direct measurement of ventilation efficiency and can be used t
o predict patient exposure to contamination. RESULTS: Although for the
room taken as a whole, ventilation efficiency was close to 50% (a val
ue corresponding to perfect mixing), the experimental results for the
local mean age of air indicate that some parts of the model were venti
lated much better than others. CONCLUSION: Room air exchange rate is o
nly one parameter useful in assessing ventilation in patient areas. Ef
fective distribution of ventilation air also is critical to the contro
l of airborne contamination. Areas of the room with poor ventilation w
ould be expected to have higher concentrations of airborne infectious
agents and other contaminants. Patient exposure can be minimized by pl
acing the patient in well-ventilated areas of the room. Improved venti
lation designs may reduce patient exposure further without increasing
actual airflow rate.