Objectives. To determine whether varicoceles are more prevalent in men
with secondary infertility than in men with primary infertility. Meth
ods. The records of 2188 consecutive men attending three infertility c
enters were reviewed to determine the incidence of varicoceles in men
with primary and secondary infertility. In addition, other factors aff
ecting both male and female infertility were assessed in these patient
s. Results. The incidence of varicoceles was not significantly differe
nt between the 1447 men with primary infertility versus the 741 men wi
th secondary infertility: 44% and 45%, respectively. The incidence of
vasal agenesis was significantly greater in men with primary infertili
ty (P < 0.001). In addition, the female partner was significantly olde
r in couples with secondary infertility (P < 0.001). Conclusions. Thes
e findings do not support the conclusion that varicoceles have a progr
essive adverse effect on fertility over time and suggest that further
study is needed to determine whether varicocele repair is indicated in
patients with normal semen parameters.