Objectives. Veno-occlusive dysfunction is a commonly diagnosed cause o
f impotence, Surgical removal of the intermediate (deep dorsal vein an
d its tributaries) venous system of the penis has been advocated as an
effective treatment but recurrence of the dysfunction is common after
a few months. We studied prospectively the first 100 cases of veno-oc
clusive dysfunction undergoing surgical treatment at our institutions.
Methods. One hundred consecutive patients undergoing penile venous li
gation surgery were evaluated, All patients had a comprehensive workup
prior to therapy. Surgery involved excision of the intermediate venou
s drainage. Short-term results were investigated by personal interview
, and long-term outcome was determined by separate telephone interview
of patients and their partners when available. Results. Short-term su
ccess (3 months) was 62%, and long-term success (45 months) was 31%. H
istorical factors, preoperative testing results, and histologic assess
ment of the surgical specimens were not found to be helpful in predict
ing outcome. Conclusions. Despite the mediocre long-term results of th
e surgical procedure and lack of preoperative predictive factors, we b
elieve that venous leak surgery could be offered to well-selected pati
ents in whom the only other available alternative would be a prostheti
c device.