ALTERATION OF THE BIOLOGICAL AND PHYSICOC HEMICAL CHARACTERISTICS OF HEMAGGLUTININ H2 OF AVIAN INFLUENZA-A VIRUS IN THE COURSE OF ADAPTATION TO A NEW HOSTS

Authors
LIPATOV AS GITELMAN AK GOVORKOVA YA SMIRNOV YA
Citation
As. Lipatov et al., ALTERATION OF THE BIOLOGICAL AND PHYSICOC HEMICAL CHARACTERISTICS OF HEMAGGLUTININ H2 OF AVIAN INFLUENZA-A VIRUS IN THE COURSE OF ADAPTATION TO A NEW HOSTS, Voprosy virusologii, 40(5), 1995, pp. 208-211
Citations number
13
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
40
Issue
5
Year of publication
1995
Pages
208 - 211
Database
ISI
SICI code
0507-4088(1995)40:5<208:AOTBAP>2.0.ZU;2-A
Abstract
Avian influenza A virus with H2 hemaeglutinin has been adapted to mice for the first time. Alterations in the hemagglutinin of adapted varia nts of the virus as a result of adaptation to a new host are described . Hemagglutinin of a highly virulent adapted variant differed from the parental avirulent strain by antigenic structure, electrophoretic mob ility, and receptor activity during interactions with murine red cells .