NUCLEOTIDE-SEQUENCE OF 2 EXONS OF CD4-REC EPTOR GENE OF HUMAN T-LYMPHOCYTES

Genome DNA encoding die N-part of human CD4 gene located in tile 15 ki lobase (kb) Sau3a restriction fragment was cloned and nucleotide seque nce of a part (3430 b.p.) of this fragment determined. Exons 2 and 3, intron 2, and partially introns 2 and 3 of this gene were located in t he sequenced fragment. Six Alu repeats and open reading frames (ORFs) coding for proteins very close to C5 and C3 components of tile complem ent were detected in this fragment.