MECHANISMS OF PROTECTIVE IMMUNE-RESPONSE IN MONKEYS WITH MARBURG FEVER

Authors
IGNATYEV GM STRELTSOVA MA AGAFONOV AP KASHENTSEVA YA
Citation
Gm. Ignatyev et al., MECHANISMS OF PROTECTIVE IMMUNE-RESPONSE IN MONKEYS WITH MARBURG FEVER, Voprosy virusologii, 40(3), 1995, pp. 109-113
Citations number
21
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
40
Issue
3
Year of publication
1995
Pages
109 - 113
Database
ISI
SICI code
0507-4088(1995)40:3<109:MOPIIM>2.0.ZU;2-L
Abstract
The parameters of nonspecific immunity (interferon, tumor necrosis met er, natural killers), of spontaneous and mitogen-induced lymphocyte pr oliferation, of specific immunity (antibodies to Marburg virus, antige n-stimulated proliferation) were found to change in the course of expe rimental Marburg fever in immune and intact animals. The named factors were shown to influence the course of the disease; their role in the lethal outcome of the infection was demonstrated.