CLINICAL AND VIROLOGICAL CHARACTERIZATION OF THE DISEASE IN GUINEA-PIGS AEROGENICALLY INFECTED WITH MARBURG VIRUS

Authors
LUB MY SERGEYEV AN PYANKOVA OG PYANKOV OV PETRISCHENKO VA KOTLYAROV LA
Citation
My. Lub et al., CLINICAL AND VIROLOGICAL CHARACTERIZATION OF THE DISEASE IN GUINEA-PIGS AEROGENICALLY INFECTED WITH MARBURG VIRUS, Voprosy virusologii, 40(3), 1995, pp. 119-121
Citations number
7
Categorie Soggetti
Virology
Journal title
Voprosy virusologii → ACNP
ISSN journal
05074088
Volume
40
Issue
3
Year of publication
1995
Pages
119 - 121
Database
ISI
SICI code
0507-4088(1995)40:3<119:CAVCOT>2.0.ZU;2-I
Abstract
Marburg virus (strain Popp) was found to accumulate in various organs of guinea pigs after aerogenic infection. At the initial stage of the infection primary multiplication of the virus took place in the lungs. The presence of the virus in bronchopulmonary washings 2-3 days after infection, leukopenia and hyperthermia 4 days after infection are the earliest virological and clinical signs of disease in aerogenically i nfected guinea pigs.