SYNTHESIS AND ANTICONVULSANT ACTIVITY OF NEW ACYLTHIOSEMICARBAZIDES AND THIAZOLIDONES

Authors
Citation
A. Gursoy et N. Karali, SYNTHESIS AND ANTICONVULSANT ACTIVITY OF NEW ACYLTHIOSEMICARBAZIDES AND THIAZOLIDONES, Il Farmaco, 50(12), 1995, pp. 857-866
Citations number
29
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
0014827X
Volume
50
Issue
12
Year of publication
1995
Pages
857 - 866
Database
ISI
SICI code
0014-827X(1995)50:12<857:SAAAON>2.0.ZU;2-X
Abstract
A number of H)-quinazolinone-2-ylmercaptoacetyl)-4-substituted thiosem icarbazide and olinone-2-ylmercaptoacetylhydrazone)-3-substituted 4-th iazolidone derivatives were synthesized and evaluated for anticonvulsa nt activity. Some of the tested compounds showed significant activity against MES and ScMet induced seizures.