FREQUENCY OF MEDIAN MONONEUROPATHY IN PATIENTS WITH MILD DIABETIC NEUROPATHY IN THE EARLY DIABETES INTERVENTION TRIAL (EDIT)

We used electrophysiologic criteria to identify median mononeuropathy (MM) at the nondominant wrist among 414 patients enrolled in a multice nter study of patients with mild diabetic neuropathy according to cons ensus recommendations. Patients with absent sural or peroneal response s or greater than mild symptoms of carpal tunnel syndrome were ineligi ble. Ninety-five of 414 participants (23%) fulfilled criteria for MM, independent of diabetes type. Patients with MM had a longer duration o f diabetes than remaining patients, independent of age, and patients w ith MM and type II diabetes were more likely to be female (34% vs. 19% ; P = 0.008), shorter (165.7 vs. 172.7 cm; P = 0.001), and have a high er body mass index (32.5 vs. 29.1; P = 0.0008) than remaining type II patients. Sural or peroneal conduction abnormalities did not influence the frequency of MM. These results suggest that patients with diabeti c neuropathy require special consideration with regard to the evaluati on of suspected carpel tunnel syndrome. (C) 1996 John Wiley & Sons, In c.