We established the frequency of Horner's syndrome (HS) in 248 elective
patients after coronary artery bypass surgery. Patients were evaluate
d neurologically pre- and post-operatively and 6 months after surgery.
Nineteen patients (7.7%) developed unilateral HS postoperatively, 12
involving the left eye. The finding persisted in 10 patients (4%) at 6
months. When assessed 2 to 6 days, or 6 months, postoperatively, HS t
ended to be isolated and not associated with C8/T1 plexopathy. Among n
ondiabetic subjects, hypertensive patients had a higher frequency of H
S than normotensive patients (10.6% versus 2.9%, p = 0.05). Among norm
otensive subjects, diabetic patients had a higher frequency than nondi
abetic patients (15% versus 2.9%, p = 0.08). There was no association
between HS, age, sex, internal mammary artery grafting, or length of c
ardiopulmonary bypass time. In summary, HS is a common and sometimes p
ersistent complication of coronary artery bypass surgery. Hypertensive
, and possibly diabetic, patients appear to be at greatest risk for de
veloping HS.