REVERSIBLE ENCEPHALOPATHY WITH CEREBRAL VASOSPASM IN A GUILLAIN-BARRE-SYNDROME PATIENT TREATED WITH INTRAVENOUS IMMUNOGLOBULIN

We report a patient with a reversible multifocal encephalopathy that d eveloped 3 days after completion of treatment with intravenous immunog lobulin for Guillain-Barre syndrome. Magnetic resonance imaging showed reversible bioccipital white matter changes, and transcranial Doppler demonstrated transiently increased flow rates in all major cerebral a rteries. We conclude that intravenous immunoglobulin therapy caused ce rebral arterial vasospasm and a reversible encephalopathy.