MELATONIN REPLACEMENT CORRECTS SLEEP DISTURBANCES IN A CHILD WITH PINEAL TUMOR

Authors
ETZIONI A LUBOSHITZKY R TIOSANO D BENHARUSH M GOLDSHER D LAVIE P
Citation
A. Etzioni et al., MELATONIN REPLACEMENT CORRECTS SLEEP DISTURBANCES IN A CHILD WITH PINEAL TUMOR, Neurology, 46(1), 1996, pp. 261-263
Citations number
10
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
46
Issue
1
Year of publication
1996
Pages
261 - 263
Database
ISI
SICI code
0028-3878(1996)46:1<261:MRCSDI>2.0.ZU;2-2
Abstract
A child with a germ cell tumor involving the pineal region had marked suppressed melatonin secretion associated with severe insomnia. Exogen ous melatonin (3 mg In the evening) for 2 weeks restored sleep continu ity, as demonstrated by objective monitoring of rest-activity cycles. This case report provides direct evidence of the essential role of mel atonin in normal sleep.