A CARBON-CARBON BOND FORMATION BY THE REACTION OF 4-CHLORO-6-METHYL-3-PHENYLETHYNYL-2H-PYRAN-2-ONE WITH ACTIVE METHYLENE DERIVATIVES

Authors
AZUMA Y SATO A MORONE M
Citation
Y. Azuma et al., A CARBON-CARBON BOND FORMATION BY THE REACTION OF 4-CHLORO-6-METHYL-3-PHENYLETHYNYL-2H-PYRAN-2-ONE WITH ACTIVE METHYLENE DERIVATIVES, Heterocycles, 42(2), 1996, pp. 789-794
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
42
Issue
2
Year of publication
1996
Pages
789 - 794
Database
ISI
SICI code
0385-5414(1996)42:2<789:ACBFBT>2.0.ZU;2-T
Abstract
The reaction of 4-chloro-6-methyl-3-phenylethynyl-2H-pyran-2-one (2) w ith compounds containing active methylene group, such as diethyl malon ate, acetylacetone, ethyl cyanoacetate, and malononitrile, in the pres ence of NaH gives 4-substituted 6-methyl-3-phenylethynyl-2H-pyran-2-on e(3) and/or 6-methyl-3-phenylacetyl-2H-pyran-2-one (5).