NEW APPROACH TO THE IMIDAZOLUTIDINE MOIETY OF MK-996

Authors
SENANAYAKE CH FREDENBURGH LE REAMER RA LIU J ROBERTS FE HUMPHREY G THOMPSON AS LARSEN RD VERHOEVEN TR REIDER PJ SHINKAI I
Citation
Ch. Senanayake et al., NEW APPROACH TO THE IMIDAZOLUTIDINE MOIETY OF MK-996, Heterocycles, 42(2), 1996, pp. 821-830
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
42
Issue
2
Year of publication
1996
Pages
821 - 830
Database
ISI
SICI code
0385-5414(1996)42:2<821:NATTIM>2.0.ZU;2-1
Abstract
A highly effective, regio-selective synthesis of imidazolutidine (1) i s described starting from readily available malonamamidine hydrochlori de and 2,4-pentanedione.