SYNTHETIC APPLICATION OF CHIRAL 4-METHOXY-2-OXAZOLIDINONE SYNTHONS TO2-AMINO ALCOHOLS OF BIOLOGICAL INTEREST

Authors
ISHIZUKA T MOROOKA K ISHIBUCHI S KUNIEDA T
Citation
T. Ishizuka et al., SYNTHETIC APPLICATION OF CHIRAL 4-METHOXY-2-OXAZOLIDINONE SYNTHONS TO2-AMINO ALCOHOLS OF BIOLOGICAL INTEREST, Heterocycles, 42(2), 1996, pp. 837-848
Citations number
34
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
42
Issue
2
Year of publication
1996
Pages
837 - 848
Database
ISI
SICI code
0385-5414(1996)42:2<837:SAOC4S>2.0.ZU;2-2
Abstract
The versatility as chiral synthons of (4S, 5S)- and (4R, 5R)-5-allyl-4 -methoxy-2-oxazolidinones, readily obtainable from )-2-exo-alkoxy-1-ap ocamphanecarbonyl]-2-oxazolone, is demonstrated by the facile stereosp ecific conversions to (2R, 3S)-3-amino-2-hydroxy-3-phenylpentanoic aci d, (2R, 3R, 5E,7E)-2-amino-5,7-tetradecadien-3-ol and (2S, 3R)-dihydro sphingosine.