Two recent advances have significantly improved the ability of labeled
red cell imaging to localize and to detect sites of active gastrointe
stinal bleeding, The first is the use of continuous dynamic imaging. T
he second is the commercial availability of an in vitro red cell label
ing method that significantly improves image quality. The computer equ
ipment required for dynamic imaging is available in most nuclear medic
ine laboratories. Because cinematic display of the dynamic images incr
eases the accuracy and ease of interpretation it should be considered
the method of choice for performing gastrointestinal bleeding studies.
High-risk patients can be identified if very active bleeding is noted
early. However, a study with negative results, after monitoring the p
atient over 1 to 2 hours, suggests that conservative medical managemen
t may be adequate. Therefore, with proper use scintigraphy can provide
both diagnostic and prognostic information to aid in the management o
f patients with gastrointestinal bleeding. (C) 1996 by W.B. Saunders C
ompany