The molecular probe data base (MPDB) contains detailed information on
synthetic oligonucleotides, including their identification, target gen
es, applications and bibliographic references. It is available on-line
through Internet and can be searched by using Network Information Ret
rieval teals. In this article the most recent enhancements of MPDB, bo
th in terms of data contents and new ways of access, are described. Th
ese include a recently established collaboration with EMBL Data Librar
y, in the sphere of SRSWWW network browser, in view of a better integr
ation of MPDB with other molecular biology databases.