HEMOPHILIA-B (6TH EDITION) - A DATABASE OF POINT MUTATIONS AND SHORT ADDITIONS AND DELETIONS

The sixth edition of the haemophilia B database lists in easily access ible form all known factor IX mutations due to small changes (base sub stitutions and short additions and/or deletions of <30 bp) identified in haemophilia B patients. The 1380 patient entries are ordered by the nucleotide number of their mutation. Where known, details are given o n factor IX activity, factor IX antigen in circulation and origin of m utation. References to published mutations are given and the laborator ies generating the data are indicated.