Jh. Meyer et al., MIDLINE GRANULOMA PRESENTING AS ORBITAL CELLULITIS, Graefe's archive for clinical and experimental ophthalmology, 234(2), 1996, pp. 137-139
Background: Lethal midline granuloma usually presents with rhinorrhoea
and redness of the skin above the nose. Early ocular symptoms are ver
y rare. We here describe a patient who presented with acute orbital ce
llulitis. Patient: A 73-year-old woman had a 24-h history of severe pa
in around her left eye. We saw the typical clinical picture of orbital
cellulitis. A CT scan revealed a diffuse infiltration of the left upp
er and lower lid, the anterior orbit and the ethmoidal sinuses. Result
: On surgical exploration we found a granular, partly necrotic tumour.
Histological examination revealed an angiocentric nasal T-cell lympho
ma (midline granuloma). Conclusion: Midline granuloma should be includ
ed in the differential diagnosis of acute orbital cellulitis.