SERIES ON STUDIES OF CEREBRAL PROTECTIVE AGENTS - PREPARATION AND PHARMACOLOGICAL EVALUATION OF 4-BENZOQUINON-2-YL)-1,2,3,4-TETRAHYDRONAPHTHALENES AS POTENT CEREBRAL PROTECTIVE AGENTS

Authors
SUZUKI K TATSUOKA T ISHIHARA T OHNO T AISAKA K OGINO R KUROKI M SATOH F MIYANO S SUMOTO K
Citation
K. Suzuki et al., SERIES ON STUDIES OF CEREBRAL PROTECTIVE AGENTS - PREPARATION AND PHARMACOLOGICAL EVALUATION OF 4-BENZOQUINON-2-YL)-1,2,3,4-TETRAHYDRONAPHTHALENES AS POTENT CEREBRAL PROTECTIVE AGENTS, Chemical and Pharmaceutical Bulletin, 44(1), 1996, pp. 132-138
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
1
Year of publication
1996
Pages
132 - 138
Database
ISI
SICI code
0009-2363(1996)44:1<132:SOSOCP>2.0.ZU;2-7
Abstract
Two new series of 4-benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes ( 3, 4) were synthesized for evaluation of their pharmacological activit ies, These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homogenate and some of them possessed a prot ective effect against hypobaric hypoxia in mice.