LIPASE-CATALYZED OPTICAL RESOLUTION OF 2-OXAZOLIDINONES

Authors
WAKAMATSU H TERAO Y
Citation
H. Wakamatsu et Y. Terao, LIPASE-CATALYZED OPTICAL RESOLUTION OF 2-OXAZOLIDINONES, Chemical and Pharmaceutical Bulletin, 44(1), 1996, pp. 261-263
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
44
Issue
1
Year of publication
1996
Pages
261 - 263
Database
ISI
SICI code
0009-2363(1996)44:1<261:LORO2>2.0.ZU;2-8
Abstract
Optically active 4- or 5-substituted 2-oxazolidinones were obtained by lipase-catalyzed enantioselective hydrolysis of the 3-acyloxymethyl-2 -oxazolidinones and transesterification of the 3-hydroxymethyl-2-oxazo lidinones with vinyl propionate in organic solvents.