HUMAN ENDOPEPTIDASE (THOP1) IS LOCALIZED ON CHROMOSOME-19 WITHIN THE LINKAGE REGION FOR THE LATE-ONSET ALZHEIMER-DISEASE AD2 LOCUS

Authors
MECKELEIN B DESILVA HAR ROSES AD RAO PN PETTENATI MJ XU PT HODGE R GLUCKSMAN MJ ABRAHAM CR
Citation
B. Meckelein et al., HUMAN ENDOPEPTIDASE (THOP1) IS LOCALIZED ON CHROMOSOME-19 WITHIN THE LINKAGE REGION FOR THE LATE-ONSET ALZHEIMER-DISEASE AD2 LOCUS, Genomics, 31(2), 1996, pp. 246-249
Citations number
27
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
31
Issue
2
Year of publication
1996
Pages
246 - 249
Database
ISI
SICI code
0888-7543(1996)31:2<246:HE(ILO>2.0.ZU;2-9
Abstract
A cDNA encoding the rat endopeptidase 24.15 was used to determine the chromosomal localization of the respective human gene. Hybridization t o DNA from human-rodent somatic cell hybrids assigned the human gene t o chromosome 19. Fluorescence in situ hybridization on human metaphase chromosomes localized the human endopeptidase 24.15 to 19q13.3. (C) 1 996 Academic Press, Inc.