H. Ogino et al., PATHOLOGY OF BOVINE ABORTION AND NEWBORN CALF DEATH CAUSED BY DUAL INFECTION WITH CHLAMYDIA-PSITTACI AND INFECTIOUS BOVINE-RHINOTRACHEITIS VIRUS, Journal of veterinary medical science, 58(1), 1996, pp. 67-70
Nine aborted fetuses and one newborn calf, diagnosed as Chlamydia psit
taci (C. psittaci) infection, were pathologically examined. The charac
teristic lesions in the liver were focal necrosis in 9 aborted fetuses
and granulomatous necrotic foci in the newborn calf. Moderate numbers
of intranuclear inclusion bodies were found in necrotic foci of the l
iver, spleen, thymus, lymph nodes, adrenal gland, kidney, lung and for
estomach. Immunohistologically, a small number of C. psittaci antigens
was demonstrated in necrotic foci of the liver and correlated with di
stribution of elementary bodies. Moderate numbers of infectious bovine
rhinotracheitis (IBR) virus antigens were also detected in degenerati
ng and necrotizing parenchymal cells in various organs and correlated
with distribution of intranuclear inclusion bodies. Thus, these aborte
d bovine fetuses and newborn calf were interpreted as being dually inf
ected with C. psittaci and IBR virus during pregnancy.