F. Dens et al., CARIES-RELATED SALIVARY MICROORGANISMS AND SALIVARY FLOW-RATE IN BONE-MARROW RECIPIENTS, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 81(1), 1996, pp. 38-43
Citations number
24
Categorie Soggetti
Pathology,Surgery,"Dentistry,Oral Surgery & Medicine
Cancer treatments often induce oral complications. In this study we in
vestigate longitudinally the salivary gland function, the salivary car
ies-related microorganisms, and buffer capacity in bone marrow recipie
nts. Stimulated saliva samples were taken midmorning. The salivary fac
tors were studied in 42 patients from before transplant until 4 months
after transplant. A dramatic reduction (66%) of salivary flow rate is
noticed in all patients at 1 month after transplant, and only a parti
al recovery (42% reduction) is seen after 4 months. A clear shift towa
rd a lower buffer capacity and a higher amount of cariogenic microorga
nisms is seen posttransplant. This shift is more pronounced when total
body irradiation was included in the pretransplant conditioning thera
py. These findings indicate that the studied parameters in transplant
recipients can contribute to a higher caries risk and oral complicatio
ns during the early posttransplant period.