An outbreak of cyptosporidiosis occurred in late April 1993 among reso
rt hotel guests which was temporally associated with, but geographical
ly distant from, a massive waterborne outbreak of cryptosporidiosis in
Milwaukee. Wisconsin, that occurred in late March and early April of
1983. A case-control study was performed among: groups with members wh
o reported illness and among a systematic sample of groups who stayed
at the resort hotel during the risk period. Of 120 persons interviewed
, 51 (43%) met the case definition. Swimming in the resort hotel's poo
l was significantly associated with case status (OR = 9.8; 95% Cl 3.4,
29.7), as was consumption of ice from the hotel's ice machines (OR =
2.3; 95% Cl 1.01, 5.2). When analysis was restricted only to laborator
y-confirmed cases and controls, swimming pool use was the only risk fa
ctor significantly associated with illness (OR = 13.0; 95% Cl 2.6, 88.
7). Following waterborne outbreaks of cryptosporidiosis associated wit
h water supplies, swimming pools should be considered as possible ongo
ing sources for transmission regionally.