The increasing prevalence of onychomycoses, along with the wider range
of organisms now recognized as potential pathogens, necessitates the
accurate laboratory identification of the specific fungus involved. Al
though the majority of infections still are caused by dermatophyte and
Candida species, many other nondermatophyte molds, such as Scytalidiu
m dimidiatum have been shown to be common agents of disease in certain
geographic areas. It is well recognized that infections by nondermato
phytes such as Scopulariopsis, Acremonium, and Aspergillus species occ
ur worldwide. The availability of a range of new antifungal agents wit
h various spectra of activity means that the exact identification of t
he pathogen is necessary to select the optimum treatment.