RHODIUM(II) CATALYZED ASYMMETRIC CYCLOPROPANATION OF GLYCALS WITH ETHYL DIAZOACETATE

Authors
TIMMERS CM LEEUWENBURGH MA VERHEIJEN JC VANDERMAREL GA VANBOOM JH
Citation
Cm. Timmers et al., RHODIUM(II) CATALYZED ASYMMETRIC CYCLOPROPANATION OF GLYCALS WITH ETHYL DIAZOACETATE, Tetrahedron : asymmetry, 7(1), 1996, pp. 49-52
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
1
Year of publication
1996
Pages
49 - 52
Database
ISI
SICI code
0957-4166(1996)7:1<49:RCACOG>2.0.ZU;2-N
Abstract
Carbenoid species generated from ethyl diazoacetate and catalytic Rh-2 (OAc)(4) react smoothly and with a high degree of stereoselectivity wi th glycals resulting in the predominant formation of doubly branched a dducts containing an alpha-exo-orientated ethyl cyclopropanecarboxylat e moiety.