ENZYMATIC GENERATION OF PLANAR CHIRALITY IN THE (ARENE)CR(CO)3 SERIES- EXPERIMENTAL RESULTS AND MODELING STUDIES

Authors
HOWELL JAS PALIN MG SALAUN J MCARDLE P CUNNINGHAM D OGARA M
Citation
Jas. Howell et al., ENZYMATIC GENERATION OF PLANAR CHIRALITY IN THE (ARENE)CR(CO)3 SERIES- EXPERIMENTAL RESULTS AND MODELING STUDIES, Tetrahedron : asymmetry, 7(1), 1996, pp. 95-104
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
1
Year of publication
1996
Pages
95 - 104
Database
ISI
SICI code
0957-4166(1996)7:1<95:EGOPCI>2.0.ZU;2-3
Abstract
Hydrolysis using pig liver esterase of (benzene-1,2-diacetic ester)Cr( CO)(3) complexes generates the half-ester in high enantiomeric purity. The high enantioselectivity may he rationalised through substrate int eraction with the Jones active site model of pig liver esterase.