CYCLIZATION OF A PRENYLATED ISOFLAVONE VIA ENZYMATIC EPOXIDATION

Authors
TANAKA M MIZUTANI J TAHARA S
Citation
M. Tanaka et al., CYCLIZATION OF A PRENYLATED ISOFLAVONE VIA ENZYMATIC EPOXIDATION, Bioscience, biotechnology, and biochemistry, 60(1), 1996, pp. 171-172
Citations number
13
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
60
Issue
1
Year of publication
1996
Pages
171 - 172
Database
ISI
SICI code
0916-8451(1996)60:1<171:COAPIV>2.0.ZU;2-5
Abstract
A cell-free system of Botrytis cinerea, which can metabolize prenylate d isoflavones into the corresponding dihydropyrano- and dihydrofurano- isoflavones, revealed the transformation to be initially catalyzed by a microsomal monooxygenase to;yield an epoxy intermediate, The enzyme activity was markedly enhanced by pretreating the mycelia with 6-preny lnaringenin, and was dependent on NADPH and O-2.