K. Iwamoto et al., RING TRANSFORMATION OF FUSED PYRIDAZINES .4. REACTION OF HALO-SUBSTITUTED FUSED PYRIDAZINES WITH YNAMINES, Heterocycles, 43(1), 1996, pp. 199-204
Halo-substituted phthalazines reacted with two equivalents of ynamines
to give penta-substituted pyridines through the N-N bond cleavage of
pyridazine moiety. And it was proved that the N-N bond cleavage reacti
on of pyridazine ring is common to halo-substituted condensed pyridazi
nes.