To ascertain the origin of biogenic amines in wine, samples were taken
in eighteen sites of the Vallee du Rhone, to determine the changes in
biogenic amines contents during the winemaking, in musts, at the end
of the alcoholic and malolactic fermentations, in marcs and lees, and
during the wine ageing process. The biogenic amines contents were dete
rmined in each sample by HPLC with precolumn derivatization and fluori
metric detection. Even if most of these amines appear during the alcoh
olic fermentation, high levels of putrescine, histamine, methylamine a
nd tyramine are developed during malolactic fermentation and wine agei
ng process, On the other hand, isoamylamine and phenylethylamine are r
ather linked to alcoholic fermentation, Very low levels of cadaverine
were found in these wines. Lees and marcs can contain high levels of b
iogenic amines.