CENTRAL PRECOCIOUS PUBERTY FOLLOWING FEMINIZING RIGHT OVARIAN GRANULOSA-CELL TUMOR

A 7-month-old girl presented with ascites and breast enlargement due t o right ovarian granulosa cell tumor, After tumor removal, the clinica l signs of incomplete precocious puberty regressed. Four years later, the patient reappeared with signs of precocious puberty, Our investiga tions proved that this was not due to tumor recurrence, but it was a t rue central precocious puberty. She responded well to therapy with a l uteinizing hormone releasing hormone agonist, and 3 years after onset of this therapy, she is growing at a normal prepubertal rate.