CASE-REPORT - UNUSUALLY HIGH-RATES OF ANEUPLOID EMBRYOS IN A 28-YEAR OLD WOMAN WITH INCONTINENTIA PIGMENTI

Authors
MUNNE S ALONSO ML GRIFO J
Citation
S. Munne et al., CASE-REPORT - UNUSUALLY HIGH-RATES OF ANEUPLOID EMBRYOS IN A 28-YEAR OLD WOMAN WITH INCONTINENTIA PIGMENTI, Cytogenetics and cell genetics, 72(1), 1996, pp. 43-45
Citations number
11
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
72
Issue
1
Year of publication
1996
Pages
43 - 45
Database
ISI
SICI code
0301-0171(1996)72:1<43:C-UHOA>2.0.ZU;2-B
Abstract
A young female carrier for incontinentia pigmenti underwent preimplant ation genetic diagnosis to prevent the transfer of affected embryos. F ISH diagnosis was performed using X, Y, 18 and 13/21 probes. Unexpecte dly, 57% of the embryos were aneuploid for these chromosomes, a rate s ignificantly higher (P < 0.005) than expected (9.3%). The patient achi eved pregnancy but spontaneously aborted a trisomy 9 fetus.