LOCALIZATION BY FLUORESCENCE IN-SITU HYBRIDIZATION OF THE HUMAN FUNCTIONAL BETA-GLUCURONIDASE GENE (GUSB) TO 7Q11.21-]Q11.22 AND 2 PSEUDOGENES TO 5P13 AND 5Q13

Authors
SPELEMAN F VERVOORT R VANROY N LIEBAERS I SLY WS LISSENS W
Citation
F. Speleman et al., LOCALIZATION BY FLUORESCENCE IN-SITU HYBRIDIZATION OF THE HUMAN FUNCTIONAL BETA-GLUCURONIDASE GENE (GUSB) TO 7Q11.21-]Q11.22 AND 2 PSEUDOGENES TO 5P13 AND 5Q13, Cytogenetics and cell genetics, 72(1), 1996, pp. 53-55
Citations number
22
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
72
Issue
1
Year of publication
1996
Pages
53 - 55
Database
ISI
SICI code
0301-0171(1996)72:1<53:LBFIHO>2.0.ZU;2-E
Abstract
The gene coding for human beta-glucuronidase (GUSB) was mapped to 7q11 .21-->q11.22 by fluorescence in situ hybridization (FISH), thus clarif ying the contradictory published localizations of this gene. Multiple unprocessed pseudogenes and pseudogene fragments for GUSB have been de scribed. However, only two weak signals, one at chromosome band 5p13 a nd the other at 5q13, could be detected with FISH, suggesting consider able divergence between GUSB and its related sequences.